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تداخل‌های دارویی

Bcg intravesical live + Cilastatin-imipenem

شدت: متوسط

Bcg intravesical live and Cilastatin-imipenem: moderate interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Intravesical BCG is a live attenuated mycobacterium that must remain viable to act. Systemic antibiotics, particularly those with antimycobacterial activity, may reduce its effect. Imipenem has limited mycobacterial activity, but BCG labeling advises postponing unnecessary antimicrobials.

معنای این تداخل به زبان ساده

Bcg intravesical live and Cilastatin-imipenem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

سطح شواهد: Low

چرا رخ می‌دهد

Antibacterial activity may reduce the viability and local immune-stimulating effect of live BCG.

اقدام لازم

Defer elective antibiotic therapy during BCG instillations where possible. If an infection requires imipenem, consider holding the instillation until treatment is complete.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bcg intravesical live و Cilastatin-imipenem، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Bcg intravesical live with Cilastatin-imipenem?

MediHelp rates the interaction as moderate. Bcg intravesical live and Cilastatin-imipenem can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Intravesical BCG is a live attenuated mycobacterium that must remain viable to act. Systemic antibiotics, particularly those with antimycobacterial activity, may reduce its effect. Imipenem has limited mycobacterial activity, but BCG labeling advises postponing unnecessary antimicrobials.

How serious is the interaction between Bcg intravesical live and Cilastatin-imipenem?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Defer elective antibiotic therapy during BCG instillations where possible. If an infection requires imipenem, consider holding the instillation until treatment is complete.

What other medicines interact with Cilastatin-imipenem?

MediHelp also lists interactions of Cilastatin-imipenem with, for example, Divalproex, Ganciclovir, Valproic acid. The full list is on the Cilastatin-imipenem page.

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