تداخل‌های دارویی
Benazepril + Empagliflozin-linagliptin
شدت: متوسط
Benazepril and Empagliflozin-linagliptin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
DPP-4 inhibitors such as linagliptin reduce breakdown of substance P and bradykinin, which are also affected by ACE inhibitors. Taking both may raise the risk of angioedema, though absolute risk remains small.
معنای این تداخل به زبان ساده
Benazepril and Empagliflozin-linagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Benazepril belongs to Cardiovascular; Empagliflozin-linagliptin belongs to Endocrine.
چرا رخ می‌دهد
Additive reduction in bradykinin and substance P degradation through ACE and DPP-4 inhibition.
اقدام لازم
Counsel the patient to report swelling of the lips, tongue or face immediately. Stop the ACE inhibitor and treat if angioedema occurs, and use an alternative antihypertensive class in patients with prior angioedema.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Benazepril و Empagliflozin-linagliptin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Empagliflozin-linagliptin
تداخلات دیگر Benazepril
پرسش‌های متداول
Can I take Benazepril with Empagliflozin-linagliptin?
MediHelp rates the interaction as moderate. Benazepril and Empagliflozin-linagliptin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. DPP-4 inhibitors such as linagliptin reduce breakdown of substance P and bradykinin, which are also affected by ACE inhibitors. Taking both may raise the risk of angioedema, though absolute risk remains small.
How serious is the interaction between Benazepril and Empagliflozin-linagliptin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Counsel the patient to report swelling of the lips, tongue or face immediately. Stop the ACE inhibitor and treat if angioedema occurs, and use an alternative antihypertensive class in patients with prior angioedema.
What other medicines interact with Empagliflozin-linagliptin?
MediHelp also lists interactions of Empagliflozin-linagliptin with, for example, Fosphenytoin, Rifampin, Rifapentine. The full list is on the Empagliflozin-linagliptin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
