تداخل‌های دارویی
Betamethasone + Ofloxacin
شدت: شدید
Betamethasone and Ofloxacin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Concurrent corticosteroid and fluoroquinolone use increases the risk of tendinitis and tendon rupture, most often of the Achilles tendon. The risk is higher in older patients and with prolonged or high-dose steroid exposure.
معنای این تداخل به زبان ساده
Betamethasone and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Betamethasone belongs to Endocrine; Ofloxacin belongs to Anti Bacterial.
چرا رخ می‌دهد
Both drug classes impair tendon collagen turnover and tenocyte function, producing additive tendon toxicity.
اقدام لازم
Avoid the combination where possible, especially in patients over 60 or with renal impairment. If used, advise the patient to stop the quinolone and rest at the first sign of tendon pain or swelling.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Betamethasone و Ofloxacin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ofloxacin
تداخلات دیگر Betamethasone
پرسش‌های متداول
Can I take Betamethasone with Ofloxacin?
MediHelp rates the interaction as major. Betamethasone and Ofloxacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Concurrent corticosteroid and fluoroquinolone use increases the risk of tendinitis and tendon rupture, most often of the Achilles tendon. The risk is higher in older patients and with prolonged or high-dose steroid exposure.
How serious is the interaction between Betamethasone and Ofloxacin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, especially in patients over 60 or with renal impairment. If used, advise the patient to stop the quinolone and rest at the first sign of tendon pain or swelling.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Thioridazine, Adagrasib, Amiodarone. The full list is on the Ofloxacin page.
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