تداخل‌های دارویی
Ofloxacin + Thioridazine
شدت: منع مصرف
Ofloxacin and Thioridazine: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Thioridazine causes marked, dose-related QT prolongation and carries a boxed warning against co-use with other QT-prolonging drugs. Adding ofloxacin further increases the risk of torsades de pointes and sudden cardiac death.
معنای این تداخل به زبان ساده
Ofloxacin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ofloxacin belongs to Anti Bacterial; Thioridazine belongs to Central Nervous System.
چرا رخ می‌دهد
Additive blockade of cardiac potassium channels on top of the strong QT-prolonging effect of thioridazine.
اقدام لازم
Avoid the combination and select an antibiotic without QT effects. If the antibiotic cannot be changed, withhold thioridazine under specialist guidance.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ofloxacin و Thioridazine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Ofloxacin
تداخلات دیگر Thioridazine
- Abiraterone + Thioridazine منع مصرف
- Adagrasib + Thioridazine منع مصرف
- Amiodarone + Thioridazine منع مصرف
- Amisulpride + Thioridazine منع مصرف
- Amitriptyline + Thioridazine منع مصرف
- Amoxapine + Thioridazine منع مصرف
پرسش‌های متداول
Can I take Ofloxacin with Thioridazine?
MediHelp rates the interaction as contraindicated. Ofloxacin and Thioridazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Thioridazine causes marked, dose-related QT prolongation and carries a boxed warning against co-use with other QT-prolonging drugs. Adding ofloxacin further increases the risk of torsades de pointes and sudden cardiac death.
How serious is the interaction between Ofloxacin and Thioridazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and select an antibiotic without QT effects. If the antibiotic cannot be changed, withhold thioridazine under specialist guidance.
What other medicines interact with Ofloxacin?
MediHelp also lists interactions of Ofloxacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Ofloxacin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
