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تداخل‌های دارویی

Bleomycin + Trastuzumab deruxtecan

شدت: شدید

Bleomycin and Trastuzumab deruxtecan: major interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Trastuzumab deruxtecan causes neutropenia and interstitial lung disease, and bleomycin carries a risk of pulmonary toxicity and some myelosuppression. Combining them may increase infection risk and lung injury.

معنای این تداخل به زبان ساده

Bleomycin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Bleomycin belongs to Oncology; Trastuzumab deruxtecan belongs to Oncology.

سطح شواهد: Low

چرا رخ می‌دهد

Additive myelosuppression and overlapping pulmonary toxicity.

اقدام لازم

Monitor blood counts and respiratory symptoms closely, and evaluate promptly any new cough or dyspnea. Avoid the combination where alternatives exist.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bleomycin و Trastuzumab deruxtecan، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Bleomycin with Trastuzumab deruxtecan?

MediHelp rates the interaction as major. Bleomycin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Trastuzumab deruxtecan causes neutropenia and interstitial lung disease, and bleomycin carries a risk of pulmonary toxicity and some myelosuppression. Combining them may increase infection risk and lung injury.

How serious is the interaction between Bleomycin and Trastuzumab deruxtecan?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood counts and respiratory symptoms closely, and evaluate promptly any new cough or dyspnea. Avoid the combination where alternatives exist.

What other medicines interact with Bleomycin?

MediHelp also lists interactions of Bleomycin with, for example, Adenovirus types 4 and 7 live, Brentuximab, Brentuximab vedotin. The full list is on the Bleomycin page.

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