رفتن به محتوا

تداخل‌های دارویی

Bupropion-naltrexone + Hydromorphone

شدت: منع مصرف

Bupropion-naltrexone and Hydromorphone: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Naltrexone blocks opioid receptors, so it antagonizes hydromorphone analgesia and can precipitate withdrawal in opioid-dependent patients. Hydromorphone is not primarily CYP2D6 dependent, so the pharmacokinetic effect of bupropion is minor by comparison.

معنای این تداخل به زبان ساده

Bupropion-naltrexone and Hydromorphone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Bupropion-naltrexone belongs to Miscellaneous; Hydromorphone belongs to Musculoskeletal.

سطح شواهد: High

چرا رخ می‌دهد

Naltrexone competitively antagonizes mu opioid receptors, opposing hydromorphone effects.

اقدام لازم

Avoid concurrent use; the product is contraindicated with chronic opioid therapy. Allow an adequate opioid-free interval before starting.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Bupropion-naltrexone و Hydromorphone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Bupropion-naltrexone with Hydromorphone?

MediHelp rates the interaction as contraindicated. Bupropion-naltrexone and Hydromorphone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Naltrexone blocks opioid receptors, so it antagonizes hydromorphone analgesia and can precipitate withdrawal in opioid-dependent patients. Hydromorphone is not primarily CYP2D6 dependent, so the pharmacokinetic effect of bupropion is minor by comparison.

How serious is the interaction between Bupropion-naltrexone and Hydromorphone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use; the product is contraindicated with chronic opioid therapy. Allow an adequate opioid-free interval before starting.

What other medicines interact with Bupropion-naltrexone?

MediHelp also lists interactions of Bupropion-naltrexone with, for example, Hydrocodone, Isocarboxazid, Linezolid. The full list is on the Bupropion-naltrexone page.

تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp

مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.

مرور از A تا Z · تداخل‌های دارویی

دریافت برنامه ورود