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Calcium Carbonate + Cholecalciferol

شدت: متوسط

Calcium Carbonate and Cholecalciferol: moderate interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Vitamin D increases intestinal calcium absorption, so combining it with calcium supplements can raise serum and urinary calcium. At usual doses the combination is intended and safe, but excessive doses or predisposing conditions can cause hypercalcemia, hypercalciuria and kidney stones.

معنای این تداخل به زبان ساده

Calcium Carbonate and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Calcium Carbonate belongs to Gastrointestinal Tract; Cholecalciferol belongs to Musculoskeletal.

سطح شواهد: High

چرا رخ می‌دهد

Pharmacodynamic: cholecalciferol, via calcitriol, enhances active intestinal calcium absorption, adding to the calcium supplied by calcium carbonate.

اقدام لازم

Use the lowest doses that meet requirements and avoid combined excessive intake from diet, supplements and fortified products. Monitor serum calcium, and urinary calcium or renal function where there is a history of stones, CKD or high-dose vitamin D.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Calcium Carbonate و Cholecalciferol، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

منابع

  • Calcium carbonate and cholecalciferol chewable tablets SmPC - Special Warnings and Interactions — EMA SmPC

پرسش‌های متداول

Can I take Calcium Carbonate with Cholecalciferol?

MediHelp rates the interaction as moderate. Calcium Carbonate and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal calcium absorption, so combining it with calcium supplements can raise serum and urinary calcium. At usual doses the combination is intended and safe, but excessive doses or predisposing conditions can cause hypercalcemia, hypercalciuria and kidney stones.

How serious is the interaction between Calcium Carbonate and Cholecalciferol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use the lowest doses that meet requirements and avoid combined excessive intake from diet, supplements and fortified products. Monitor serum calcium, and urinary calcium or renal function where there is a history of stones, CKD or high-dose vitamin D.

What other medicines interact with Calcium Carbonate?

MediHelp also lists interactions of Calcium Carbonate with, for example, Acalabrutinib, Alendronate, Amlodipine-hydrochlorothiazide-valsartan. The full list is on the Calcium Carbonate page.

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