تداخلهای دارویی
Aluminum hydroxide + Cholecalciferol
شدت: متوسط
Aluminum hydroxide and Cholecalciferol: moderate interaction.
آخرین بهروزرسانی
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خلاصه
Vitamin D increases intestinal absorption of aluminum, and chronic use of aluminum-containing antacids can lead to aluminum accumulation. This is most important in renal impairment, where aluminum toxicity can cause bone disease and neurotoxicity.
معنای این تداخل به زبان ساده
Aluminum hydroxide and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Cholecalciferol belongs to Musculoskeletal.
چرا رخ میدهد
Vitamin D enhances gastrointestinal aluminum absorption, and aluminum is poorly excreted in renal failure.
اقدام لازم
Avoid long-term aluminum antacids in patients taking vitamin D, particularly with renal impairment; use a non-aluminum alternative.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Aluminum hydroxide و Cholecalciferol، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cholecalciferol
تداخلات دیگر Aluminum hydroxide
پرسشهای متداول
Can I take Aluminum hydroxide with Cholecalciferol?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Cholecalciferol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D increases intestinal absorption of aluminum, and chronic use of aluminum-containing antacids can lead to aluminum accumulation. This is most important in renal impairment, where aluminum toxicity can cause bone disease and neurotoxicity.
How serious is the interaction between Aluminum hydroxide and Cholecalciferol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid long-term aluminum antacids in patients taking vitamin D, particularly with renal impairment; use a non-aluminum alternative.
What other medicines interact with Cholecalciferol?
MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Calcium acetate, Calcium Carbonate. The full list is on the Cholecalciferol page.
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