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تداخل‌های دارویی

Cangrelor + Warfarin

شدت: متوسط

Cangrelor and Warfarin: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.

معنای این تداخل به زبان ساده

Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cangrelor belongs to Cardiovascular; Warfarin belongs to Cardiovascular.

سطح شواهد: Moderate

چرا رخ می‌دهد

Additive pharmacodynamic effect of P2Y12 platelet inhibition and vitamin K antagonist anticoagulation.

اقدام لازم

Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cangrelor و Warfarin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cangrelor with Warfarin?

MediHelp rates the interaction as moderate. Cangrelor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cangrelor is an intravenous P2Y12 inhibitor with a very short action. With warfarin, bleeding risk increases while it is infused, because platelet and coagulation pathways are both inhibited.

How serious is the interaction between Cangrelor and Warfarin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for bleeding and hemoglobin during and after the infusion, and check INR as needed. Reassess the need for combined antithrombotic therapy.

What other medicines interact with Warfarin?

MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.

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