تداخل‌های دارویی
Caplacizumab + Dabigatran etexilate
شدت: شدید
Caplacizumab and Dabigatran etexilate: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Caplacizumab blocks von Willebrand factor-platelet binding and impairs primary hemostasis, and dabigatran adds anticoagulant effect. Together they increase the risk of serious bleeding.
معنای این تداخل به زبان ساده
Caplacizumab and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Caplacizumab belongs to Cardiovascular; Dabigatran etexilate belongs to Cardiovascular.
چرا رخ می‌دهد
Additive hemostatic impairment: antiplatelet-like vWF inhibition plus direct thrombin inhibition.
اقدام لازم
Avoid concurrent use where possible; if anticoagulation is essential, monitor closely for bleeding and consider holding dabigatran during caplacizumab treatment. Withhold both before invasive procedures per labeling.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Caplacizumab و Dabigatran etexilate، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Dabigatran etexilate
تداخلات دیگر Caplacizumab
پرسش‌های متداول
Can I take Caplacizumab with Dabigatran etexilate?
MediHelp rates the interaction as major. Caplacizumab and Dabigatran etexilate can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Caplacizumab blocks von Willebrand factor-platelet binding and impairs primary hemostasis, and dabigatran adds anticoagulant effect. Together they increase the risk of serious bleeding.
How serious is the interaction between Caplacizumab and Dabigatran etexilate?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use where possible; if anticoagulation is essential, monitor closely for bleeding and consider holding dabigatran during caplacizumab treatment. Withhold both before invasive procedures per labeling.
What other medicines interact with Dabigatran etexilate?
MediHelp also lists interactions of Dabigatran etexilate with, for example, Defibrotide, Ketorolac, Mifepristone. The full list is on the Dabigatran etexilate page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
