تداخل‌های دارویی
Cefepime + Plazomicin
شدت: متوسط
Cefepime and Plazomicin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Plazomicin is an aminoglycoside with known nephrotoxicity, ototoxicity and neuromuscular blockade risk, and both drugs depend on renal elimination. Combining with cefepime may add to renal stress, and any decline in kidney function would increase plazomicin exposure and cefepime-related neurotoxicity.
معنای این تداخل به زبان ساده
Cefepime and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cefepime belongs to Anti Bacterial; Plazomicin belongs to Anti Bacterial.
چرا رخ می‌دهد
Additive potential nephrotoxicity with reduced renal clearance of both drugs if kidney injury occurs.
اقدام لازم
Monitor serum creatinine and plazomicin concentrations per labeling, and adjust doses of both drugs to renal function. Assess hearing and neurologic status during therapy.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefepime و Plazomicin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cefepime
- Amikacin + Cefepime متوسط
- Cefepime + Cholera vaccine متوسط
- Cefepime + Dexamethasone-tobramycin متوسط
- Cefepime + Gentamicin متوسط
- Cefepime + Kanamycin متوسط
- Cefepime + Microbiota متوسط
تداخلات دیگر Plazomicin
- Cefaclor + Plazomicin متوسط
- Cefadroxil + Plazomicin متوسط
- Cefalexin + Plazomicin متوسط
- Cefazolin + Plazomicin متوسط
- Cefditoren + Plazomicin متوسط
- Cefixime + Plazomicin متوسط
پرسش‌های متداول
Can I take Cefepime with Plazomicin?
MediHelp rates the interaction as moderate. Cefepime and Plazomicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Plazomicin is an aminoglycoside with known nephrotoxicity, ototoxicity and neuromuscular blockade risk, and both drugs depend on renal elimination. Combining with cefepime may add to renal stress, and any decline in kidney function would increase plazomicin exposure and cefepime-related neurotoxicity.
How serious is the interaction between Cefepime and Plazomicin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and plazomicin concentrations per labeling, and adjust doses of both drugs to renal function. Assess hearing and neurologic status during therapy.
What other medicines interact with Cefepime?
MediHelp also lists interactions of Cefepime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Cefepime page.
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