Ceftazidime + Sodium picosulfate / magnesium oxide / anhydrous citric acid

MediHelp rates the interaction as moderate. Ceftazidime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug activated by colonic bacteria, so antibiotics that disrupt colonic flora may reduce its laxative effect. Parenteral ceftazidime reaches the colon less than oral antibiotics, but poor bowel cleansing before colonoscopy is possible.

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess bowel preparation adequacy and consider additional or alternative cleansing if the preparation seems inadequate. Where possible, avoid starting antibiotics during the preparation period.

MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.