تداخلهای دارویی
Cyclobenzaprine + Glycopyrrolate
شدت: متوسط
Cyclobenzaprine and Glycopyrrolate: moderate interaction.
آخرین بهروزرسانی
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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Both drugs have antimuscarinic activity, so combining them increases anticholinergic effects such as dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older adults and patients with glaucoma, prostatic hypertrophy or ileus are at greatest risk.
معنای این تداخل به زبان ساده
Cyclobenzaprine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Cyclobenzaprine belongs to Musculoskeletal; Glycopyrrolate belongs to Respiratory.
چرا رخ میدهد
Additive blockade of muscarinic receptors by cyclobenzaprine and glycopyrrolate.
اقدام لازم
Monitor for anticholinergic adverse effects such as urinary retention, constipation and confusion, and reduce the dose or choose an alternative if they emerge. Avoid in patients with narrow-angle glaucoma or obstructive uropathy.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیههای کامل مدیریت Cyclobenzaprine و Glycopyrrolate، یادداشتهای تکمیلی، جزئیات شواهد و بررسیکننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Cyclobenzaprine
- Cyclobenzaprine + Isocarboxazid منع مصرف
- Cyclobenzaprine + Linezolid منع مصرف
- Cyclobenzaprine + Phenelzine منع مصرف
- Cyclobenzaprine + Safinamide منع مصرف
- Cyclobenzaprine + Selegiline منع مصرف
- Cyclobenzaprine + Selegiline transdermal منع مصرف
تداخلات دیگر Glycopyrrolate
پرسشهای متداول
Can I take Cyclobenzaprine with Glycopyrrolate?
MediHelp rates the interaction as moderate. Cyclobenzaprine and Glycopyrrolate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs have antimuscarinic activity, so combining them increases anticholinergic effects such as dry mouth, constipation, urinary retention, blurred vision and tachycardia. Older adults and patients with glaucoma, prostatic hypertrophy or ileus are at greatest risk.
How serious is the interaction between Cyclobenzaprine and Glycopyrrolate?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic adverse effects such as urinary retention, constipation and confusion, and reduce the dose or choose an alternative if they emerge. Avoid in patients with narrow-angle glaucoma or obstructive uropathy.
What other medicines interact with Cyclobenzaprine?
MediHelp also lists interactions of Cyclobenzaprine with, for example, Isocarboxazid, Linezolid, Phenelzine. The full list is on the Cyclobenzaprine page.
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