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تداخل‌های دارویی

Deflazacort + Influenza virus vaccine quadrivalent intranasal

شدت: منع مصرف

Deflazacort and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.

معنای این تداخل به زبان ساده

Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Glucocorticoid immunosuppression impairs clearance of live attenuated virus and the vaccine immune response.

اقدام لازم

Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Deflazacort و Influenza virus vaccine quadrivalent intranasal، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Deflazacort with Influenza virus vaccine quadrivalent intranasal?

MediHelp rates the interaction as contraindicated. Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.

How serious is the interaction between Deflazacort and Influenza virus vaccine quadrivalent intranasal?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.

تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp

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