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تداخل‌های دارویی

Deflazacort + Measles mumps rubella and varicella vaccine live

شدت: منع مصرف

Deflazacort and Measles mumps rubella and varicella vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.

معنای این تداخل به زبان ساده

Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.

اقدام لازم

Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Deflazacort و Measles mumps rubella and varicella vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Deflazacort with Measles mumps rubella and varicella vaccine live?

MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.

How serious is the interaction between Deflazacort and Measles mumps rubella and varicella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

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