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تداخل‌های دارویی

Deflazacort + Measles mumps and rubella vaccine live

شدت: منع مصرف

Deflazacort and Measles mumps and rubella vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.

معنای این تداخل به زبان ساده

Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.

اقدام لازم

Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Deflazacort و Measles mumps and rubella vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Deflazacort with Measles mumps and rubella vaccine live?

MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps and rubella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The live attenuated MMR viruses may replicate excessively in patients immunosuppressed by deflazacort, risking vaccine-strain disease. The immune response may also be reduced.

How serious is the interaction between Deflazacort and Measles mumps and rubella vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during immunosuppressive corticosteroid therapy; give at least four weeks before starting steroids or after stopping for the interval in labeling. Check immunity and consider immunoglobulin after exposure.

What other medicines interact with Deflazacort?

MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.

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