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تداخل‌های دارویی

Desogestrel-ethinyl estradiol + Elagolix

شدت: شدید

Desogestrel-ethinyl estradiol and Elagolix: major interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Elagolix lowers estrogen levels, while estrogen-containing contraceptives are expected to oppose this effect and reduce its efficacy. Elagolix is also not a reliable contraceptive and may reduce hormonal contraceptive exposure.

معنای این تداخل به زبان ساده

Desogestrel-ethinyl estradiol and Elagolix can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Desogestrel-ethinyl estradiol belongs to Endocrine; Elagolix belongs to Musculoskeletal.

سطح شواهد: Moderate

چرا رخ می‌دهد

Pharmacodynamic antagonism between exogenous estrogen and elagolix-induced estrogen suppression.

اقدام لازم

Avoid estrogen-containing contraceptives and use non-hormonal contraception during elagolix therapy and for 1 week after stopping.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Desogestrel-ethinyl estradiol و Elagolix، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Desogestrel-ethinyl estradiol with Elagolix?

MediHelp rates the interaction as major. Desogestrel-ethinyl estradiol and Elagolix can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Elagolix lowers estrogen levels, while estrogen-containing contraceptives are expected to oppose this effect and reduce its efficacy. Elagolix is also not a reliable contraceptive and may reduce hormonal contraceptive exposure.

How serious is the interaction between Desogestrel-ethinyl estradiol and Elagolix?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid estrogen-containing contraceptives and use non-hormonal contraception during elagolix therapy and for 1 week after stopping.

What other medicines interact with Desogestrel-ethinyl estradiol?

MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.

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