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تداخل‌های دارویی

Dexamethasone + Varicella virus vaccine live

شدت: منع مصرف

Dexamethasone and Varicella virus vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.

معنای این تداخل به زبان ساده

Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: High

چرا رخ می‌دهد

Glucocorticoid-induced suppression of cellular immunity permits uncontrolled replication of the attenuated virus.

اقدام لازم

Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dexamethasone و Varicella virus vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Dexamethasone with Varicella virus vaccine live?

MediHelp rates the interaction as contraindicated. Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.

How serious is the interaction between Dexamethasone and Varicella virus vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.

What other medicines interact with Dexamethasone?

MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.

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