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تداخل‌های دارویی

Dexamethasone + Zoster vaccine live

شدت: منع مصرف

Dexamethasone and Zoster vaccine live: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Live zoster vaccine contains replicating varicella-zoster virus, which may cause disseminated disease in patients on immunosuppressive doses of dexamethasone. The immune response to the vaccine may also be reduced.

معنای این تداخل به زبان ساده

Dexamethasone and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Glucocorticoid-induced suppression of cell-mediated immunity allows replication of the attenuated virus.

اقدام لازم

Do not give live zoster vaccine during high-dose corticosteroid therapy; wait at least 1 month after stopping. Use the recombinant non-live zoster vaccine where available.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dexamethasone و Zoster vaccine live، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Dexamethasone with Zoster vaccine live?

MediHelp rates the interaction as contraindicated. Dexamethasone and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live zoster vaccine contains replicating varicella-zoster virus, which may cause disseminated disease in patients on immunosuppressive doses of dexamethasone. The immune response to the vaccine may also be reduced.

How serious is the interaction between Dexamethasone and Zoster vaccine live?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live zoster vaccine during high-dose corticosteroid therapy; wait at least 1 month after stopping. Use the recombinant non-live zoster vaccine where available.

What other medicines interact with Dexamethasone?

MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.

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