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Dexmethylphenidate + Rasagiline

شدت: منع مصرف

Dexmethylphenidate and Rasagiline: contraindicated interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.

معنای این تداخل به زبان ساده

Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dexmethylphenidate belongs to Central Nervous System; Rasagiline belongs to Central Nervous System.

سطح شواهد: High

چرا رخ می‌دهد

Dexmethylphenidate increases synaptic catecholamines and MAO inhibition prevents their breakdown, causing additive pressor effects.

اقدام لازم

Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Dexmethylphenidate و Rasagiline، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Dexmethylphenidate with Rasagiline?

MediHelp rates the interaction as contraindicated. Dexmethylphenidate and Rasagiline are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Stimulants such as dexmethylphenidate given with MAO inhibitors may cause hypertensive crisis. Labeling contraindicates use during and for 14 days after MAO inhibitor therapy.

How serious is the interaction between Dexmethylphenidate and Rasagiline?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and separate by at least 14 days after stopping the MAO inhibitor. Use a non-stimulant alternative if needed.

What other medicines interact with Rasagiline?

MediHelp also lists interactions of Rasagiline with, for example, Atomoxetine, Brimonidine, Bupropion-naltrexone. The full list is on the Rasagiline page.

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