تداخل‌های دارویی
Econazole + Warfarin
شدت: متوسط
Econazole and Warfarin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Topical econazole applied over large areas, to genital skin or under occlusive dressings can be absorbed enough to raise the INR in patients taking warfarin. Bleeding episodes have been reported with azole antifungals used this way.
معنای این تداخل به زبان ساده
Econazole and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Econazole belongs to Anti Fungals; Warfarin belongs to Cardiovascular.
چرا رخ می‌دهد
Systemically absorbed econazole inhibits CYP2C9 and other CYP enzymes, reducing clearance of the more potent S-warfarin.
اقدام لازم
Check INR within several days of starting econazole, particularly with extensive, genital or occluded application, and adjust the warfarin dose as needed. Limit the treated area where possible.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Econazole و Warfarin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Warfarin
- Defibrotide + Warfarin منع مصرف
- Ketorolac + Warfarin منع مصرف
- Abciximab + Warfarin شدید
- Acetylsalicylic acid + Warfarin شدید
- Adagrasib + Warfarin شدید
- Amiodarone + Warfarin شدید
پرسش‌های متداول
Can I take Econazole with Warfarin?
MediHelp rates the interaction as moderate. Econazole and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Topical econazole applied over large areas, to genital skin or under occlusive dressings can be absorbed enough to raise the INR in patients taking warfarin. Bleeding episodes have been reported with azole antifungals used this way.
How serious is the interaction between Econazole and Warfarin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within several days of starting econazole, particularly with extensive, genital or occluded application, and adjust the warfarin dose as needed. Limit the treated area where possible.
What other medicines interact with Warfarin?
MediHelp also lists interactions of Warfarin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Warfarin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
