تداخل‌های دارویی
Eluxadoline + Loperamide
شدت: شدید
Eluxadoline and Loperamide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Eluxadoline is a gut-acting opioid agonist and loperamide also slows gut motility, so together they raise the risk of severe constipation. Serious outcomes include ileus and pancreatitis-related complications noted in eluxadoline labeling.
معنای این تداخل به زبان ساده
Eluxadoline and Loperamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Eluxadoline belongs to Gastrointestinal Tract; Loperamide belongs to Gastrointestinal Tract.
چرا رخ می‌دهد
Additive opioid receptor-mediated reduction in gastrointestinal motility.
اقدام لازم
Avoid chronic loperamide use with eluxadoline; occasional use for severe acute diarrhea is acceptable. Stop loperamide immediately if constipation develops.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Eluxadoline و Loperamide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Loperamide
تداخلات دیگر Eluxadoline
پرسش‌های متداول
Can I take Eluxadoline with Loperamide?
MediHelp rates the interaction as major. Eluxadoline and Loperamide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eluxadoline is a gut-acting opioid agonist and loperamide also slows gut motility, so together they raise the risk of severe constipation. Serious outcomes include ileus and pancreatitis-related complications noted in eluxadoline labeling.
How serious is the interaction between Eluxadoline and Loperamide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid chronic loperamide use with eluxadoline; occasional use for severe acute diarrhea is acceptable. Stop loperamide immediately if constipation develops.
What other medicines interact with Loperamide?
MediHelp also lists interactions of Loperamide with, for example, Amiodarone, Amisulpride, Anagrelide. The full list is on the Loperamide page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
