تداخل‌های دارویی
Eluxadoline + Morphine
شدت: شدید
Eluxadoline and Morphine: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Eluxadoline is a mu-opioid agonist used for diarrhea-predominant IBS and is labeled to be avoided with drugs that cause constipation. Morphine's constipating effect may lead to severe constipation or complications such as ileus, and eluxadoline-related pancreatitis risk is also a concern.
معنای این تداخل به زبان ساده
Eluxadoline and Morphine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Eluxadoline belongs to Gastrointestinal Tract; Morphine belongs to Musculoskeletal.
چرا رخ می‌دهد
Additive opioid-receptor-mediated reduction in gastrointestinal motility.
اقدام لازم
Avoid the combination; if opioid therapy is needed, stop eluxadoline. Monitor for constipation and abdominal pain if exposure overlaps.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Eluxadoline و Morphine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Morphine
- Alvimopan + Morphine منع مصرف
- Isocarboxazid + Morphine منع مصرف
- Morphine + Olanzapine / samidorphan منع مصرف
- Morphine + Phenelzine منع مصرف
- Morphine + Tranylcypromine منع مصرف
- Alfentanil + Morphine شدید
تداخلات دیگر Eluxadoline
پرسش‌های متداول
Can I take Eluxadoline with Morphine?
MediHelp rates the interaction as major. Eluxadoline and Morphine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eluxadoline is a mu-opioid agonist used for diarrhea-predominant IBS and is labeled to be avoided with drugs that cause constipation. Morphine's constipating effect may lead to severe constipation or complications such as ileus, and eluxadoline-related pancreatitis risk is also a concern.
How serious is the interaction between Eluxadoline and Morphine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination; if opioid therapy is needed, stop eluxadoline. Monitor for constipation and abdominal pain if exposure overlaps.
What other medicines interact with Morphine?
MediHelp also lists interactions of Morphine with, for example, Alvimopan, Isocarboxazid, Olanzapine / samidorphan. The full list is on the Morphine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
