تداخل‌های دارویی
Epirubicin + Trastuzumab deruxtecan
شدت: شدید
Epirubicin and Trastuzumab deruxtecan: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Trastuzumab-based therapy can cause cardiomyopathy and left ventricular dysfunction, and the risk is highest when given with anthracyclines. Epirubicin adds its own dose-related cardiotoxicity, and trastuzumab deruxtecan also carries risk of interstitial lung disease and myelosuppression.
معنای این تداخل به زبان ساده
Epirubicin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Epirubicin belongs to Oncology; Trastuzumab deruxtecan belongs to Oncology.
چرا رخ می‌دهد
Additive cardiotoxicity from HER2 inhibition and anthracycline-induced myocardial injury.
اقدام لازم
Avoid concurrent use when possible and keep the interval between agents as long as practical. Check left ventricular ejection fraction before and during treatment.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Epirubicin و Trastuzumab deruxtecan، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Epirubicin
تداخلات دیگر Trastuzumab deruxtecan
پرسش‌های متداول
Can I take Epirubicin with Trastuzumab deruxtecan?
MediHelp rates the interaction as major. Epirubicin and Trastuzumab deruxtecan can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Trastuzumab-based therapy can cause cardiomyopathy and left ventricular dysfunction, and the risk is highest when given with anthracyclines. Epirubicin adds its own dose-related cardiotoxicity, and trastuzumab deruxtecan also carries risk of interstitial lung disease and myelosuppression.
How serious is the interaction between Epirubicin and Trastuzumab deruxtecan?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use when possible and keep the interval between agents as long as practical. Check left ventricular ejection fraction before and during treatment.
What other medicines interact with Epirubicin?
MediHelp also lists interactions of Epirubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cimetidine. The full list is on the Epirubicin page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
