تداخل‌های دارویی
Fluvoxamine + Methylene blue
شدت: منع مصرف
Fluvoxamine and Methylene blue: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Methylene blue is a potent reversible MAO-A inhibitor, and with serotonergic drugs such as fluvoxamine it can cause serious serotonin syndrome. Cases have occurred with intravenous doses used for methemoglobinemia or vasoplegia.
معنای این تداخل به زبان ساده
Fluvoxamine and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
چرا رخ می‌دهد
MAO-A inhibition by methylene blue combined with serotonin reuptake inhibition by fluvoxamine causes excess serotonin.
اقدام لازم
Avoid combined use; where methylene blue is urgently needed, stop fluvoxamine and monitor for serotonin toxicity for an extended period, noting that fluvoxamine's washout is relatively short compared with fluoxetine.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Fluvoxamine و Methylene blue، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Fluvoxamine
- Agomelatine + Fluvoxamine منع مصرف
- Alosetron + Fluvoxamine منع مصرف
- Fezolinetant + Fluvoxamine منع مصرف
- Fluvoxamine + Isocarboxazid منع مصرف
- Fluvoxamine + Mavacamten منع مصرف
- Fluvoxamine + Phenelzine منع مصرف
پرسش‌های متداول
Can I take Fluvoxamine with Methylene blue?
MediHelp rates the interaction as contraindicated. Fluvoxamine and Methylene blue are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Methylene blue is a potent reversible MAO-A inhibitor, and with serotonergic drugs such as fluvoxamine it can cause serious serotonin syndrome. Cases have occurred with intravenous doses used for methemoglobinemia or vasoplegia.
How serious is the interaction between Fluvoxamine and Methylene blue?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid combined use; where methylene blue is urgently needed, stop fluvoxamine and monitor for serotonin toxicity for an extended period, noting that fluvoxamine's washout is relatively short compared with fluoxetine.
What other medicines interact with Fluvoxamine?
MediHelp also lists interactions of Fluvoxamine with, for example, Agomelatine, Alosetron, Fezolinetant. The full list is on the Fluvoxamine page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
