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تداخل‌های دارویی

Heparin + Ketorolac

شدت: منع مصرف

Heparin and Ketorolac: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Ketorolac inhibits platelet function and can cause GI bleeding, and heparin is an anticoagulant, so serious bleeding risk is markedly higher. Ketorolac labeling contraindicates its use in patients at risk of bleeding, including those receiving anticoagulants.

معنای این تداخل به زبان ساده

Heparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Heparin belongs to Cardiovascular; Ketorolac belongs to Musculoskeletal.

سطح شواهد: High

چرا رخ می‌دهد

Additive hemostatic impairment from NSAID platelet inhibition and heparin-mediated antithrombin potentiation.

اقدام لازم

Avoid ketorolac in patients on therapeutic heparin and use a non-NSAID analgesic; if exposure occurs, monitor for bleeding and hemoglobin and aPTT.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Heparin و Ketorolac، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Heparin with Ketorolac?

MediHelp rates the interaction as contraindicated. Heparin and Ketorolac are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Ketorolac inhibits platelet function and can cause GI bleeding, and heparin is an anticoagulant, so serious bleeding risk is markedly higher. Ketorolac labeling contraindicates its use in patients at risk of bleeding, including those receiving anticoagulants.

How serious is the interaction between Heparin and Ketorolac?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid ketorolac in patients on therapeutic heparin and use a non-NSAID analgesic; if exposure occurs, monitor for bleeding and hemoglobin and aPTT.

What other medicines interact with Ketorolac?

MediHelp also lists interactions of Ketorolac with, for example, Aceclofenac, Acemetacin, Acetylsalicylic acid. The full list is on the Ketorolac page.

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