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تداخل‌های دارویی

Heparin + Oritavancin

شدت: منع مصرف

Heparin and Oritavancin: contraindicated interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Oritavancin artificially prolongs aPTT for many days, so unfractionated heparin monitoring becomes unreliable. This may lead to inappropriate dosing and bleeding or thrombosis.

معنای این تداخل به زبان ساده

Heparin and Oritavancin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Heparin belongs to Cardiovascular; Oritavancin belongs to Anti Bacterial.

سطح شواهد: High

چرا رخ می‌دهد

Oritavancin binds phospholipid reagents used in coagulation assays, causing laboratory interference rather than a true pharmacodynamic effect.

اقدام لازم

Avoid IV unfractionated heparin for the period stated in labeling after oritavancin. Use an alternative anticoagulant monitored by a non-aPTT method if needed.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Heparin و Oritavancin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Heparin with Oritavancin?

MediHelp rates the interaction as contraindicated. Heparin and Oritavancin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oritavancin artificially prolongs aPTT for many days, so unfractionated heparin monitoring becomes unreliable. This may lead to inappropriate dosing and bleeding or thrombosis.

How serious is the interaction between Heparin and Oritavancin?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid IV unfractionated heparin for the period stated in labeling after oritavancin. Use an alternative anticoagulant monitored by a non-aPTT method if needed.

What other medicines interact with Oritavancin?

MediHelp also lists interactions of Oritavancin with, for example, Warfarin, Carbamazepine, Cyclosporin. The full list is on the Oritavancin page.

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