تداخل‌های دارویی
Hydrocodone + Phenelzine
شدت: منع مصرف
Hydrocodone and Phenelzine: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
MAOIs combined with opioids can cause serotonin syndrome or severe opioid toxicity including respiratory depression and coma. Labeling advises against opioid use during and for 14 days after MAOI therapy.
معنای این تداخل به زبان ساده
Hydrocodone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Hydrocodone belongs to Musculoskeletal; Phenelzine belongs to Central Nervous System.
چرا رخ می‌دهد
Inhibition of monoamine oxidase raises serotonergic and noradrenergic activity, with possible potentiation of opioid CNS effects.
اقدام لازم
Avoid hydrocodone during MAOI therapy and for 14 days after stopping. Choose a non-serotonergic analgesic strategy and monitor closely if an opioid is unavoidable.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Hydrocodone و Phenelzine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Hydrocodone
- Alvimopan + Hydrocodone منع مصرف
- Bupropion-naltrexone + Hydrocodone منع مصرف
- Hydrocodone + Isocarboxazid منع مصرف
- Hydrocodone + Olanzapine / samidorphan منع مصرف
- Alfentanil + Hydrocodone شدید
- Alprazolam + Hydrocodone شدید
تداخلات دیگر Phenelzine
- 5-HTP + Phenelzine منع مصرف
- Amitriptyline + Phenelzine منع مصرف
- Amoxapine + Phenelzine منع مصرف
- Atomoxetine + Phenelzine منع مصرف
- Benzphetamine + Phenelzine منع مصرف
- Brimonidine + Phenelzine منع مصرف
پرسش‌های متداول
Can I take Hydrocodone with Phenelzine?
MediHelp rates the interaction as contraindicated. Hydrocodone and Phenelzine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MAOIs combined with opioids can cause serotonin syndrome or severe opioid toxicity including respiratory depression and coma. Labeling advises against opioid use during and for 14 days after MAOI therapy.
How serious is the interaction between Hydrocodone and Phenelzine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid hydrocodone during MAOI therapy and for 14 days after stopping. Choose a non-serotonergic analgesic strategy and monitor closely if an opioid is unavoidable.
What other medicines interact with Hydrocodone?
MediHelp also lists interactions of Hydrocodone with, for example, Alvimopan, Bupropion-naltrexone, Isocarboxazid. The full list is on the Hydrocodone page.
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