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تداخل‌های دارویی

Insulin aspart-insulin aspart protamine + Rosiglitazone

شدت: شدید

Insulin aspart-insulin aspart protamine and Rosiglitazone: major interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Rosiglitazone with insulin increases the risk of hypoglycemia, fluid retention, edema and heart failure. The combination is generally discouraged because of cardiovascular concerns.

معنای این تداخل به زبان ساده

Insulin aspart-insulin aspart protamine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Insulin aspart-insulin aspart protamine belongs to Endocrine; Rosiglitazone belongs to Endocrine.

سطح شواهد: High

چرا رخ می‌دهد

Additive glucose lowering through PPAR-gamma insulin sensitization with insulin; both contribute to fluid retention.

اقدام لازم

Avoid in patients with heart failure or high cardiac risk. If used, monitor for fluid retention and glucose and reduce insulin as needed.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin aspart-insulin aspart protamine و Rosiglitazone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Insulin aspart-insulin aspart protamine with Rosiglitazone?

MediHelp rates the interaction as major. Insulin aspart-insulin aspart protamine and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone with insulin increases the risk of hypoglycemia, fluid retention, edema and heart failure. The combination is generally discouraged because of cardiovascular concerns.

How serious is the interaction between Insulin aspart-insulin aspart protamine and Rosiglitazone?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients with heart failure or high cardiac risk. If used, monitor for fluid retention and glucose and reduce insulin as needed.

What other medicines interact with Insulin aspart-insulin aspart protamine?

MediHelp also lists interactions of Insulin aspart-insulin aspart protamine with, for example, Ethanol, Pentamidine, Pioglitazone. The full list is on the Insulin aspart-insulin aspart protamine page.

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