تداخل‌های دارویی
Insulin degludec-liraglutide + Rosiglitazone
شدت: شدید
Insulin degludec-liraglutide and Rosiglitazone: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Rosiglitazone improves insulin sensitivity, and combining it with insulin and liraglutide adds to the glucose-lowering effect and the risk of hypoglycemia. Rosiglitazone with insulin also increases the risk of edema and heart failure.
معنای این تداخل به زبان ساده
Insulin degludec-liraglutide and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec-liraglutide belongs to Endocrine; Rosiglitazone belongs to Endocrine.
چرا رخ می‌دهد
Additive glucose lowering from insulin sensitization combined with insulin and GLP-1 receptor agonism, with thiazolidinedione-related fluid retention.
اقدام لازم
Avoid the combination where possible, particularly in patients with or at risk of heart failure. If used, monitor glucose, reduce the insulin dose as needed and watch for edema and weight gain.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin degludec-liraglutide و Rosiglitazone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin degludec-liraglutide
تداخلات دیگر Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone شدید
- Insulin aspart-insulin aspart protamine + Rosiglitazone شدید
- Insulin aspart + Rosiglitazone شدید
- Insulin degludec / insulin aspart + Rosiglitazone شدید
- Insulin degludec-insulin aspart + Rosiglitazone شدید
- Insulin degludec + Rosiglitazone شدید
پرسش‌های متداول
Can I take Insulin degludec-liraglutide with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec-liraglutide and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone improves insulin sensitivity, and combining it with insulin and liraglutide adds to the glucose-lowering effect and the risk of hypoglycemia. Rosiglitazone with insulin also increases the risk of edema and heart failure.
How serious is the interaction between Insulin degludec-liraglutide and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible, particularly in patients with or at risk of heart failure. If used, monitor glucose, reduce the insulin dose as needed and watch for edema and weight gain.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
