تداخل‌های دارویی
Insulin degludec + Rosiglitazone
شدت: شدید
Insulin degludec and Rosiglitazone: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Rosiglitazone improves insulin sensitivity and enhances insulin's glucose-lowering effect, increasing hypoglycemia risk. Combination with insulin has also been associated with fluid retention, heart failure and possibly myocardial ischemia.
معنای این تداخل به زبان ساده
Insulin degludec and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec belongs to Endocrine; Rosiglitazone belongs to Endocrine.
چرا رخ می‌دهد
Additive glucose lowering from insulin sensitization plus exogenous insulin; fluid retention is also additive.
اقدام لازم
Monitor blood glucose and reduce the insulin dose as needed. Monitor for edema and heart failure signs, and avoid in patients with heart failure or high cardiovascular risk.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin degludec و Rosiglitazone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin degludec
تداخلات دیگر Rosiglitazone
- Insulin aspart protamine / insulin aspart + Rosiglitazone شدید
- Insulin aspart-insulin aspart protamine + Rosiglitazone شدید
- Insulin aspart + Rosiglitazone شدید
- Insulin degludec / insulin aspart + Rosiglitazone شدید
- Insulin degludec-insulin aspart + Rosiglitazone شدید
- Insulin degludec-liraglutide + Rosiglitazone شدید
پرسش‌های متداول
Can I take Insulin degludec with Rosiglitazone?
MediHelp rates the interaction as major. Insulin degludec and Rosiglitazone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Rosiglitazone improves insulin sensitivity and enhances insulin's glucose-lowering effect, increasing hypoglycemia risk. Combination with insulin has also been associated with fluid retention, heart failure and possibly myocardial ischemia.
How serious is the interaction between Insulin degludec and Rosiglitazone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and reduce the insulin dose as needed. Monitor for edema and heart failure signs, and avoid in patients with heart failure or high cardiovascular risk.
What other medicines interact with Insulin degludec?
MediHelp also lists interactions of Insulin degludec with, for example, Alogliptin-pioglitazone, Ethanol, Glimepiride-pioglitazone. The full list is on the Insulin degludec page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
