تداخل‌های دارویی
Insulin degludec-insulin aspart + Mecasermin
شدت: شدید
Insulin degludec-insulin aspart and Mecasermin: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Mecasermin is recombinant IGF-1 and has insulin-like glucose-lowering activity, so combining it with insulin can cause additive and sometimes severe hypoglycemia.
معنای این تداخل به زبان ساده
Insulin degludec-insulin aspart and Mecasermin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Insulin degludec-insulin aspart belongs to Endocrine; Mecasermin belongs to Endocrine.
چرا رخ می‌دهد
Additive pharmacodynamic effect: IGF-1 acts on insulin receptors and IGF-1 receptors to lower blood glucose.
اقدام لازم
Give mecasermin with or shortly after a meal and monitor blood glucose closely. Reduce the insulin dose as needed.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Insulin degludec-insulin aspart و Mecasermin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Insulin degludec-insulin aspart
تداخلات دیگر Mecasermin
پرسش‌های متداول
Can I take Insulin degludec-insulin aspart with Mecasermin?
MediHelp rates the interaction as major. Insulin degludec-insulin aspart and Mecasermin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Mecasermin is recombinant IGF-1 and has insulin-like glucose-lowering activity, so combining it with insulin can cause additive and sometimes severe hypoglycemia.
How serious is the interaction between Insulin degludec-insulin aspart and Mecasermin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give mecasermin with or shortly after a meal and monitor blood glucose closely. Reduce the insulin dose as needed.
What other medicines interact with Insulin degludec-insulin aspart?
MediHelp also lists interactions of Insulin degludec-insulin aspart with, for example, Chlorpropamide, Clozapine, Diazoxide. The full list is on the Insulin degludec-insulin aspart page.
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