تداخل‌های دارویی
Mifepristone + Prednisone
شدت: منع مصرف
Mifepristone and Prednisone: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Mifepristone is a glucocorticoid receptor antagonist and can blunt the effect of corticosteroids. In patients on long-term corticosteroids this may precipitate adrenal insufficiency or loss of disease control, and labeling for the abortion indication lists chronic corticosteroid therapy as a contraindication.
معنای این تداخل به زبان ساده
Mifepristone and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Mifepristone belongs to Endocrine; Prednisone belongs to Endocrine.
چرا رخ می‌دهد
Mifepristone antagonizes glucocorticoid receptors, opposing the effect of prednisone.
اقدام لازم
Do not use mifepristone in patients on long-term corticosteroid therapy. If a patient needs both, an alternative strategy should be selected by a specialist, since usual steroid doses may be ineffective.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Mifepristone و Prednisone، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Prednisone
تداخلات دیگر Mifepristone
- Apixaban + Mifepristone منع مصرف
- Argatroban + Mifepristone منع مصرف
- Cisapride + Mifepristone منع مصرف
- Cortisone + Mifepristone منع مصرف
- Cyclosporin + Mifepristone منع مصرف
- Dabigatran etexilate + Mifepristone منع مصرف
پرسش‌های متداول
Can I take Mifepristone with Prednisone?
MediHelp rates the interaction as contraindicated. Mifepristone and Prednisone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is a glucocorticoid receptor antagonist and can blunt the effect of corticosteroids. In patients on long-term corticosteroids this may precipitate adrenal insufficiency or loss of disease control, and labeling for the abortion indication lists chronic corticosteroid therapy as a contraindication.
How serious is the interaction between Mifepristone and Prednisone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use mifepristone in patients on long-term corticosteroid therapy. If a patient needs both, an alternative strategy should be selected by a specialist, since usual steroid doses may be ineffective.
What other medicines interact with Prednisone?
MediHelp also lists interactions of Prednisone with, for example, Bcg vaccine live, Measles vaccine, Radium-223 dichloride. The full list is on the Prednisone page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
