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تداخل‌های دارویی

Prednisone + Radium-223 dichloride

شدت: منع مصرف

Prednisone and Radium-223 dichloride: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.

معنای این تداخل به زبان ساده

Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Prednisone belongs to Endocrine; Radium-223 dichloride belongs to Miscellaneous.

سطح شواهد: Low

چرا رخ می‌دهد

The mechanism is not established; additive bone toxicity has been proposed.

اقدام لازم

Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Prednisone و Radium-223 dichloride، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Prednisone with Radium-223 dichloride?

MediHelp rates the interaction as contraindicated. Prednisone and Radium-223 dichloride are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Prednisone is relevant here as the steroid given with abiraterone; that triple combination with radium-223 has shown more fractures and a mortality trend. Prednisone alone with radium-223 is not itself the identified concern.

How serious is the interaction between Prednisone and Radium-223 dichloride?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid radium-223 in patients receiving abiraterone with prednisone. Review need for steroids and bone protection if used separately.

What other medicines interact with Radium-223 dichloride?

MediHelp also lists interactions of Radium-223 dichloride with, for example, Abiraterone, Prednisolone, Siponimod. The full list is on the Radium-223 dichloride page.

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