Référentiel des médicaments
Miltefosine
Miltefosine is a medicine in the class anti parasitic. It is used for leishmaniasis.
- Classe médicamenteuse: Anti Parasitic
- Indications: leishmaniasis
Dernière mise à jour Sources: US FDA label
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L'essentiel
- Classe médicamenteuse
- Anti Parasitic
- Formes courantes
- gélule
- Dosages courants
- 50 mg
- Noms commerciaux
- 2
- Pays et marchés
- 1
Indications
Mécanisme d'action
Miltefosine is an anti-leishmanial agent.
Posologie adulte habituelle (résumé de la notice)
Visceral, cutaneous and mucosal leishmaniasis, weight 30 kg to 44 kg: one 50 mg capsule orally twice daily with food (breakfast and dinner) for 28 consecutive days
Grossesse et allaitement
- Grossesse
- Unsafe Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing.
- Allaitement
- Unsafe Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
Effets indésirables signalés
- Vomiting
- Nausea
- Diarrhea
- Decreased appetite
- Headache
- Dizziness
Mises en garde encadrées
- Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose. Do not give to pregnant women. Obtain a serum or urine pregnancy test in females of reproductive potential before prescribing. Advise effective contraception during therapy and for 5 months after therapy.
Contre-indications
- Pregnancy
- Sjögren-Larsson-Syndrome
- Hypersensitivity to miltefosine or any of its excipients
Précautions particulières
- Reproductive effects: testicular atrophy and impaired fertility in male rats and impaired fertility in female rats; effects on human fertility not adequately evaluated.
- Renal effects: serum creatinine elevations; monitor renal function weekly during therapy and for 4 weeks after.
- Hepatic effects: monitor ALT, AST and bilirubin during therapy.
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
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- Renal and hepatic dose adjustments
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Questions fréquentes
What is Miltefosine used for?
Miltefosine is a medicine in the class anti parasitic. It is used for Leishmaniasis.
What side effects have been reported with Miltefosine?
Vomiting, Nausea, Diarrhea, Decreased appetite, Headache, Dizziness. Serious warning: Embryo-fetal toxicity: may cause fetal harm; fetal death and teratogenicity occurred in animals at doses lower than the recommended human dose.
Can Miltefosine be taken in pregnancy or while breastfeeding?
Pregnancy: Unsafe. Contraindicated; may cause fetal harm with embryo-fetal toxicity and teratogenicity in animals. Pregnancy test required before prescribing. Breastfeeding: Unsafe. Not known if present in human milk; breastfeeding should be avoided during therapy and for 5 months after.
What does Miltefosine interact with?
MediHelp does not list a checked interaction for Miltefosine yet. Always tell your pharmacist about every medicine you take.
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