Référentiel des médicaments
Naratriptan
Naratriptan is a medicine in the class central nervous system. It is used for migraine.
- Classe médicamenteuse: Central Nervous System
- Indications: migraine
Dernière mise à jour
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L'essentiel
- Classe médicamenteuse
- Central Nervous System
- Formes courantes
- comprimé
- Dosages courants
- 2.5 mg
- Interactions connues
- 113 (Contre-indiquée: 8 · Majeure: 11 · Modérée: 69 · Mineure: 25)
- Noms commerciaux
- 3
- Pays et marchés
- 2
Indications
Mécanisme d'action
Selective 5-HT1 receptor agonist in cranial arteries Causes vasoconstriction and reduces inflammation associated with antidronic neuronal transmission associated with relief of migraine
Posologie adulte habituelle (résumé de la notice)
1-2.5 mg PO at onset; may repeat once after 4 hours, Not to exceed 5 mg/day
Grossesse et allaitement
- Grossesse
- Unknown Small registry and cohort data are too few to judge, though triptan registries (mainly sumatriptan) show no rise in birth defects. In animals it caused embryo death and fetal abnormalities at 2.5 to 11 times human exposure. Use only if needed; sumatriptan has the most pregnancy data.
- Allaitement
- Unknown No human milk data; present in rat milk. UK label: avoid breastfeeding for 24 hours after a dose. Triptans can occasionally cause painful nipples. LactMed: not a reason to stop breastfeeding an older infant, but an alternative may be preferred with a newborn.
Effets indésirables signalés
- Drowsiness
- Fatigue
- Nausea
- Dizziness
- Paresthesias
- Pain/pressure sensation
Précautions particulières
- Reports of transient and permanent blindness and significant partial vision loss reported with the use of 5-HT1 agonists; since visual disorders may be part of a migraine
- Life-threatening disturbances of cardiac rhythm, including ventricular tachycardia and ventricular fibrillation leading to death
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (113)
- Almotriptan + Naratriptan Contraindicated
- Dihydroergotamine + Naratriptan Contraindicated
- Dihydroergotamine intranasal + Naratriptan Contraindicated
- Eletriptan + Naratriptan Contraindicated
- Ergoloid mesylates + Naratriptan Contraindicated
- Ergotamine + Naratriptan Contraindicated
- Frovatriptan + Naratriptan Contraindicated
- Methylergonovine + Naratriptan Contraindicated
- Isocarboxazid + Naratriptan Major
- Linezolid + Naratriptan Major
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Questions fréquentes
What is Naratriptan used for?
Naratriptan is a medicine in the class central nervous system. It is used for Migraine.
What side effects have been reported with Naratriptan?
Drowsiness, Fatigue, Nausea, Dizziness, Paresthesias, Pain/pressure sensation.
Can Naratriptan be taken in pregnancy or while breastfeeding?
Pregnancy: Unknown. Small registry and cohort data are too few to judge, though triptan registries (mainly sumatriptan) show no rise in birth defects. In animals it caused embryo death and fetal abnormalities at 2.5 to 11 times human exposure. Use only if needed; sumatriptan has the most pregnancy data. Breastfeeding: Unknown. No human milk data; present in rat milk. UK label: avoid breastfeeding for 24 hours after a dose. Triptans can occasionally cause painful nipples. LactMed: not a reason to stop breastfeeding an older infant, but an alternative may be preferred with a newborn.
What does Naratriptan interact with?
MediHelp lists 113 known interactions for Naratriptan. Contraindicated: 8 · Major: 11 · Moderate: 69 · Minor: 25. The most serious include Almotriptan, Dihydroergotamine, Dihydroergotamine intranasal.
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