Interactions médicamenteuses
Abacavir + Nevirapine
Gravité: Mineure
Abacavir and Nevirapine: minor interaction.
Dernière mise à jour
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Résumé
Nevirapine and abacavir are commonly used together in HIV regimens and no pharmacokinetic interaction is of concern. Both may be followed by immune reconstitution inflammatory syndrome when therapy starts, but this is a feature of antiretroviral initiation rather than a drug interaction. Both drugs can cause hypersensitivity reactions, which can be confused clinically.
Ce que signifie cette interaction, en termes simples
Abacavir and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Abacavir belongs to Anti Virals; Nevirapine belongs to Anti Virals.
Pourquoi elle survient
No established interaction; immune recovery after antiretroviral initiation causes IRIS, and both drugs carry hypersensitivity risk.
Conduite à tenir
Monitor for inflammatory symptoms and rash or fever during the first weeks of therapy. Confirm HLA-B*5701 status before abacavir use.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Nevirapine
- Elbasvir / grazoprevir + Nevirapine Contre-indiquée
- Nevirapine + Ranolazine Contre-indiquée
- Nevirapine + St john's wort Contre-indiquée
- Abemaciclib + Nevirapine Majeure
- Acalabrutinib + Nevirapine Majeure
- Amobarbital + Nevirapine Majeure
Autres interactions de Abacavir
- Abacavir + Ribavirin Modérée
- Abacavir + Efavirenz Mineure
- Abacavir + Emtricitabine Mineure
- Abacavir + Ganciclovir Mineure
- Abacavir + Methadone Mineure
- Abacavir + Valganciclovir Mineure
Questions fréquentes
Can I take Abacavir with Nevirapine?
MediHelp rates the interaction as minor. Abacavir and Nevirapine have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Nevirapine and abacavir are commonly used together in HIV regimens and no pharmacokinetic interaction is of concern. Both may be followed by immune reconstitution inflammatory syndrome when therapy starts, but this is a feature of antiretroviral initiation rather than a drug interaction. Both drugs can cause hypersensitivity reactions, which can be confused clinically.
How serious is the interaction between Abacavir and Nevirapine?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for inflammatory symptoms and rash or fever during the first weeks of therapy. Confirm HLA-B*5701 status before abacavir use.
What other medicines interact with Nevirapine?
MediHelp also lists interactions of Nevirapine with, for example, Elbasvir / grazoprevir, Ranolazine, St john's wort. The full list is on the Nevirapine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
