Interactions médicamenteuses
Abacavir + Methadone
Gravité: Mineure
Abacavir and Methadone: minor interaction.
Dernière mise à jour
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Résumé
Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
Ce que signifie cette interaction, en termes simples
Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Abacavir belongs to Anti Virals; Methadone belongs to Musculoskeletal.
Pourquoi elle survient
Possible modest increase in methadone clearance; the exact mechanism is not established.
Conduite à tenir
Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Methadone
- Alvimopan + Methadone Contre-indiquée
- Calcium / magnesium / potassium / sodium oxybates + Methadone Contre-indiquée
- Droperidol + Methadone Contre-indiquée
- Ibutilide + Methadone Contre-indiquée
- Isocarboxazid + Methadone Contre-indiquée
- Lefamulin + Methadone Contre-indiquée
Autres interactions de Abacavir
- Abacavir + Ribavirin Modérée
- Abacavir + Efavirenz Mineure
- Abacavir + Emtricitabine Mineure
- Abacavir + Ganciclovir Mineure
- Abacavir + Nevirapine Mineure
- Abacavir + Valganciclovir Mineure
Questions fréquentes
Can I take Abacavir with Methadone?
MediHelp rates the interaction as minor. Abacavir and Methadone have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Abacavir may modestly increase methadone clearance, which could occasionally lead to reduced opioid effect or withdrawal symptoms. In studies the changes in methadone exposure were small and dose adjustment was generally not needed.
How serious is the interaction between Abacavir and Methadone?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for withdrawal symptoms or reduced effect after starting abacavir and increase the methadone dose only if clinically needed.
What other medicines interact with Methadone?
MediHelp also lists interactions of Methadone with, for example, Alvimopan, Calcium / magnesium / potassium / sodium oxybates, Droperidol. The full list is on the Methadone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
