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Interactions médicamenteuses

Abrocitinib + Ticlopidine

Gravité: Majeure

Abrocitinib and Ticlopidine: major interaction.

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Résumé

Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.

Ce que signifie cette interaction, en termes simples

Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Abrocitinib belongs to Miscellaneous; Ticlopidine belongs to Cardiovascular.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive impairment of platelet function and count.

Conduite à tenir

Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Abrocitinib with Ticlopidine?

MediHelp rates the interaction as major. Abrocitinib and Ticlopidine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Abrocitinib lowers platelet count and function early in treatment, and ticlopidine also impairs platelet function and can cause thrombocytopenia. Together they increase bleeding risk. Labeling advises against antiplatelets except low-dose aspirin in the first three months.

How serious is the interaction between Abrocitinib and Ticlopidine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination in the first three months of abrocitinib. Monitor platelet counts and for bleeding if it cannot be avoided.

What other medicines interact with Ticlopidine?

MediHelp also lists interactions of Ticlopidine with, for example, Mavacamten, Acetylsalicylic acid, Apixaban. The full list is on the Ticlopidine page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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