Interactions médicamenteuses
Acetylsalicylic acid + Caplacizumab
Gravité: Majeure
Acetylsalicylic acid and Caplacizumab: major interaction.
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Résumé
Caplacizumab inhibits von Willebrand factor-mediated platelet adhesion, and aspirin inhibits platelet aggregation, so combined use increases the risk of bleeding. Aspirin is sometimes used alongside caplacizumab in aTTP, but bleeding such as epistaxis and gingival bleeding is more likely.
Ce que signifie cette interaction, en termes simples
Acetylsalicylic acid and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Acetylsalicylic acid belongs to Musculoskeletal; Caplacizumab belongs to Cardiovascular.
Pourquoi elle survient
Additive impairment of platelet function and primary hemostasis via different pathways.
Conduite à tenir
Monitor closely for bleeding and hold caplacizumab before any invasive procedure. Use aspirin only when clearly indicated and review the need if bleeding occurs.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Acetylsalicylic acid
- Acetylsalicylic acid + Ketorolac Contre-indiquée
- Acetylsalicylic acid + Ketorolac intranasal Contre-indiquée
- Abciximab + Acetylsalicylic acid Majeure
- Acemetacin + Acetylsalicylic acid Majeure
- Acetazolamide + Acetylsalicylic acid Majeure
- Acetylsalicylic acid + Alteplase Majeure
Autres interactions de Caplacizumab
- Abciximab + Caplacizumab Majeure
- Alteplase + Caplacizumab Majeure
- Anagrelide + Caplacizumab Majeure
- Apixaban + Caplacizumab Majeure
- Argatroban + Caplacizumab Majeure
- Caplacizumab + Clopidogrel Majeure
Questions fréquentes
Can I take Acetylsalicylic acid with Caplacizumab?
MediHelp rates the interaction as major. Acetylsalicylic acid and Caplacizumab can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Caplacizumab inhibits von Willebrand factor-mediated platelet adhesion, and aspirin inhibits platelet aggregation, so combined use increases the risk of bleeding. Aspirin is sometimes used alongside caplacizumab in aTTP, but bleeding such as epistaxis and gingival bleeding is more likely.
How serious is the interaction between Acetylsalicylic acid and Caplacizumab?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor closely for bleeding and hold caplacizumab before any invasive procedure. Use aspirin only when clearly indicated and review the need if bleeding occurs.
What other medicines interact with Acetylsalicylic acid?
MediHelp also lists interactions of Acetylsalicylic acid with, for example, Ketorolac, Ketorolac intranasal, Abciximab. The full list is on the Acetylsalicylic acid page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
