Interactions médicamenteuses
Aluminum hydroxide + Chenodeoxycholic acid
Gravité: Modérée
Aluminum hydroxide and Chenodeoxycholic acid: moderate interaction.
Dernière mise à jour
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Résumé
Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
Ce que signifie cette interaction, en termes simples
Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Aluminum hydroxide belongs to Gastrointestinal Tract; Chenodeoxycholic acid belongs to Gastrointestinal Tract.
Pourquoi elle survient
Adsorption of bile acid by aluminium hydroxide in the intestinal lumen reduces absorption.
Conduite à tenir
Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Chenodeoxycholic acid
Autres interactions de Aluminum hydroxide
Questions fréquentes
Can I take Aluminum hydroxide with Chenodeoxycholic acid?
MediHelp rates the interaction as moderate. Aluminum hydroxide and Chenodeoxycholic acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Aluminium-containing antacids can adsorb bile acids in the gut. This reduces absorption of chenodeoxycholic acid and may weaken its therapeutic effect.
How serious is the interaction between Aluminum hydroxide and Chenodeoxycholic acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Separate the doses by at least 2 hours. Monitor clinical or biochemical response if concomitant use continues.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Colestipol. The full list is on the Chenodeoxycholic acid page.
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