Interactions médicamenteuses
Chenodeoxycholic acid + Colestipol
Gravité: Modérée
Chenodeoxycholic acid and Colestipol: moderate interaction.
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Résumé
Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
Ce que signifie cette interaction, en termes simples
Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Chenodeoxycholic acid belongs to Gastrointestinal Tract; Colestipol belongs to Cardiovascular.
Pourquoi elle survient
Colestipol binds chenodeoxycholic acid in the gut, preventing absorption and enterohepatic recirculation.
Conduite à tenir
Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Chenodeoxycholic acid
Autres interactions de Colestipol
- Amlodipine-hydrochlorothiazide-valsartan + Colestipol Modérée
- Amlodipine-olmesartan-hydrochlorothiazide + Colestipol Modérée
- Atenolol-chlorthalidone + Colestipol Modérée
- Azilsartan-chlorthalidone + Colestipol Modérée
- Candesartan-hydrochlorothiazide + Colestipol Modérée
- Captopril-hydrochlorothiazide + Colestipol Modérée
Questions fréquentes
Can I take Chenodeoxycholic acid with Colestipol?
MediHelp rates the interaction as moderate. Chenodeoxycholic acid and Colestipol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Colestipol is a bile acid sequestrant that binds bile acids in the intestine. It reduces absorption of chenodeoxycholic acid and may lessen its efficacy.
How serious is the interaction between Chenodeoxycholic acid and Colestipol?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give chenodeoxycholic acid at least 2 hours before or after colestipol. Monitor response, or choose an alternative lipid-lowering agent.
What other medicines interact with Chenodeoxycholic acid?
MediHelp also lists interactions of Chenodeoxycholic acid with, for example, Cyclosporin, Sirolimus, Aluminum hydroxide. The full list is on the Chenodeoxycholic acid page.
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