Interactions médicamenteuses
Amlodipine-perindopril + Protein a column
Gravité: Contre-indiquée
Amlodipine-perindopril and Protein a column: contraindicated interaction.
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Résumé
ACE inhibitor-treated patients undergoing protein A immunoadsorption have experienced anaphylactoid reactions, related to bradykinin accumulation.
Ce que signifie cette interaction, en termes simples
Amlodipine-perindopril and Protein a column are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
ACE inhibition prevents bradykinin breakdown, so bradykinin accumulates during column exposure and triggers anaphylactoid reactions.
Conduite à tenir
Stop perindopril well before the procedure (about 72 hours per labeling) and use another antihypertensive class meanwhile.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Amlodipine-perindopril
- Aliskiren + Amlodipine-perindopril Contre-indiquée
- Amlodipine-perindopril + Sacubitril / valsartan Contre-indiquée
- Amifostine + Amlodipine-perindopril Majeure
- Amiloride + Amlodipine-perindopril Majeure
- Amlodipine-perindopril + Azilsartan Majeure
- Amlodipine-perindopril + Candesartan Majeure
Questions fréquentes
Can I take Amlodipine-perindopril with Protein a column?
MediHelp rates the interaction as contraindicated. Amlodipine-perindopril and Protein a column are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. ACE inhibitor-treated patients undergoing protein A immunoadsorption have experienced anaphylactoid reactions, related to bradykinin accumulation.
How serious is the interaction between Amlodipine-perindopril and Protein a column?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Stop perindopril well before the procedure (about 72 hours per labeling) and use another antihypertensive class meanwhile.
What other medicines interact with Amlodipine-perindopril?
MediHelp also lists interactions of Amlodipine-perindopril with, for example, Aliskiren, Sacubitril / valsartan, Amifostine. The full list is on the Amlodipine-perindopril page.
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