Aller au contenu
MediHelp
MediHelp Référence médicamenteuse

Interactions médicamenteuses

Amobarbital + Levonorgestrel

Gravité: Majeure

Amobarbital and Levonorgestrel: major interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Barbiturates can lower levonorgestrel concentrations and may cause contraceptive failure, including with emergency contraception.

Ce que signifie cette interaction, en termes simples

Amobarbital and Levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Amobarbital belongs to Central Nervous System; Levonorgestrel belongs to Endocrine.

Niveau de preuve: Moderate

Pourquoi elle survient

Barbiturate induction of CYP3A4 accelerates levonorgestrel metabolism.

Conduite à tenir

Use an additional non-hormonal method or a non-affected method such as a copper IUD; for emergency contraception, consider a copper IUD or a higher levonorgestrel dose per local guidance.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Amobarbital et Levonorgestrel, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription
Créer un compte gratuit Se connecter

Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.

Questions fréquentes

Can I take Amobarbital with Levonorgestrel?

MediHelp rates the interaction as major. Amobarbital and Levonorgestrel can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Barbiturates can lower levonorgestrel concentrations and may cause contraceptive failure, including with emergency contraception.

How serious is the interaction between Amobarbital and Levonorgestrel?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use an additional non-hormonal method or a non-affected method such as a copper IUD; for emergency contraception, consider a copper IUD or a higher levonorgestrel dose per local guidance.

What other medicines interact with Amobarbital?

MediHelp also lists interactions of Amobarbital with, for example, Calcium / magnesium / potassium / sodium oxybates, Doravirine, Elbasvir / grazoprevir. The full list is on the Amobarbital page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Télécharger surApp Store Disponible surGoogle Play

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter