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Interactions médicamenteuses

Amoxicillin-clavulanic acid + Eravacycline

Gravité: Modérée

Amoxicillin-clavulanic acid and Eravacycline: moderate interaction.

Dernière mise à jour

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Résumé

Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.

Ce que signifie cette interaction, en termes simples

Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amoxicillin-clavulanic acid belongs to Anti Bacterial; Eravacycline belongs to Anti Bacterial.

Niveau de preuve: Low

Pourquoi elle survient

Pharmacodynamic antagonism: growth suppression by a protein synthesis inhibitor reduces beta-lactam bactericidal activity.

Conduite à tenir

Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Amoxicillin-clavulanic acid with Eravacycline?

MediHelp rates the interaction as moderate. Amoxicillin-clavulanic acid and Eravacycline can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Eravacycline is a bacteriostatic tetracycline-class antibiotic that could theoretically antagonize beta-lactam killing. Clinical data on this combination are scarce. It matters mainly in severe infections where bactericidal activity is needed.

How serious is the interaction between Amoxicillin-clavulanic acid and Eravacycline?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unnecessary combination and use the narrowest effective regimen. If both are needed, monitor clinical and microbiological response.

What other medicines interact with Amoxicillin-clavulanic acid?

MediHelp also lists interactions of Amoxicillin-clavulanic acid with, for example, Methotrexate, Pexidartinib, Pretomanid. The full list is on the Amoxicillin-clavulanic acid page.

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