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Interactions médicamenteuses

Anagrelide + Solifenacin

Gravité: Majeure

Anagrelide and Solifenacin: major interaction.

Dernière mise à jour

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Résumé

Both drugs can prolong the QT interval, so co-use may increase the risk of ventricular arrhythmias such as torsades de pointes. Anagrelide can also cause tachycardia and palpitations.

Ce que signifie cette interaction, en termes simples

Anagrelide and Solifenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Anagrelide belongs to Cardiovascular; Solifenacin belongs to Genitourinary.

Niveau de preuve: Low

Pourquoi elle survient

Additive QT prolongation through pharmacodynamic effects.

Conduite à tenir

Avoid if possible or obtain a baseline ECG and monitor it, keeping potassium and magnesium within normal range.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anagrelide with Solifenacin?

MediHelp rates the interaction as major. Anagrelide and Solifenacin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can prolong the QT interval, so co-use may increase the risk of ventricular arrhythmias such as torsades de pointes. Anagrelide can also cause tachycardia and palpitations.

How serious is the interaction between Anagrelide and Solifenacin?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid if possible or obtain a baseline ECG and monitor it, keeping potassium and magnesium within normal range.

What other medicines interact with Solifenacin?

MediHelp also lists interactions of Solifenacin with, for example, Adagrasib, Amiodarone, Amisulpride. The full list is on the Solifenacin page.

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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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