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Interactions médicamenteuses

Antithymocyte globulin equine + Pneumococcal vaccine 13-valent

Gravité: Modérée

Antithymocyte globulin equine and Pneumococcal vaccine 13-valent: moderate interaction.

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Résumé

Equine antithymocyte globulin depletes T cells and may markedly reduce the response to pneumococcal conjugate vaccine, though the vaccine is safe.

Ce que signifie cette interaction, en termes simples

Antithymocyte globulin equine and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Niveau de preuve: Moderate

Pourquoi elle survient

Profound T-cell depletion impairs T-cell-dependent antibody production.

Conduite à tenir

Delay elective vaccination until lymphocyte recovery; vaccinate earlier only if the infection risk is high, then check response.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Antithymocyte globulin equine with Pneumococcal vaccine 13-valent?

MediHelp rates the interaction as moderate. Antithymocyte globulin equine and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Equine antithymocyte globulin depletes T cells and may markedly reduce the response to pneumococcal conjugate vaccine, though the vaccine is safe.

How serious is the interaction between Antithymocyte globulin equine and Pneumococcal vaccine 13-valent?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Delay elective vaccination until lymphocyte recovery; vaccinate earlier only if the infection risk is high, then check response.

What other medicines interact with Pneumococcal vaccine 13-valent?

MediHelp also lists interactions of Pneumococcal vaccine 13-valent with, for example, Adalimumab, Alefacept, Anakinra. The full list is on the Pneumococcal vaccine 13-valent page.

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