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Interactions médicamenteuses

Anti-thymocyte + Pneumococcal vaccine 13-valent

Gravité: Modérée

Anti-thymocyte and Pneumococcal vaccine 13-valent: moderate interaction.

Dernière mise à jour

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Résumé

Patients treated with anti-thymocyte may mount a weaker antibody response to pneumococcal vaccine 13-valent. Protection can therefore be incomplete, although the inactivated vaccine itself is safe to give.

Ce que signifie cette interaction, en termes simples

Anti-thymocyte and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Anti-thymocyte belongs to Miscellaneous; Pneumococcal vaccine 13-valent belongs to Miscellaneous.

Niveau de preuve: Moderate

Pourquoi elle survient

Immunosuppression blunts vaccine-induced antibody production

Conduite à tenir

Give inactivated vaccines anyway, ideally before starting the immunosuppressant, and consider checking titres or repeating doses.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Anti-thymocyte with Pneumococcal vaccine 13-valent?

MediHelp rates the interaction as moderate. Anti-thymocyte and Pneumococcal vaccine 13-valent can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Patients treated with anti-thymocyte may mount a weaker antibody response to pneumococcal vaccine 13-valent. Protection can therefore be incomplete, although the inactivated vaccine itself is safe to give.

How serious is the interaction between Anti-thymocyte and Pneumococcal vaccine 13-valent?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give inactivated vaccines anyway, ideally before starting the immunosuppressant, and consider checking titres or repeating doses.

What other medicines interact with Anti-thymocyte?

MediHelp also lists interactions of Anti-thymocyte with, for example, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Anti-thymocyte page.

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