Interactions médicamenteuses
Apixaban + Eptifibatide
Gravité: Majeure
Apixaban and Eptifibatide: major interaction.
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Résumé
Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.
Ce que signifie cette interaction, en termes simples
Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Apixaban belongs to Cardiovascular; Eptifibatide belongs to Cardiovascular.
Pourquoi elle survient
Additive hemostatic impairment from platelet aggregation blockade and factor Xa inhibition.
Conduite à tenir
Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Apixaban
- Apixaban + Dabigatran Contre-indiquée
- Apixaban + Defibrotide Contre-indiquée
- Apixaban + Edoxaban Contre-indiquée
- Apixaban + Ketorolac Contre-indiquée
- Apixaban + Mifepristone Contre-indiquée
- Abciximab + Apixaban Majeure
Autres interactions de Eptifibatide
- Abrocitinib + Eptifibatide Majeure
- Acalabrutinib + Eptifibatide Majeure
- Acetylsalicylic acid + Eptifibatide Majeure
- Antithrombin alfa + Eptifibatide Majeure
- Antithrombin iii + Eptifibatide Majeure
- Argatroban + Eptifibatide Majeure
Questions fréquentes
Can I take Apixaban with Eptifibatide?
MediHelp rates the interaction as major. Apixaban and Eptifibatide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Eptifibatide blocks platelet glycoprotein IIb/IIIa receptors and, with apixaban, substantially increases the risk of serious bleeding. It is used in acute coronary settings where anticoagulation overlap may occur.
How serious is the interaction between Apixaban and Eptifibatide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid unless clearly necessary; if combined, monitor closely for bleeding and check hemoglobin and renal function. Consider holding apixaban during the infusion per the treating cardiology team.
What other medicines interact with Apixaban?
MediHelp also lists interactions of Apixaban with, for example, Dabigatran, Defibrotide, Edoxaban. The full list is on the Apixaban page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
