Interactions médicamenteuses
Artemether / lumefantrine + Octreotide
Gravité: Majeure
Artemether / lumefantrine and Octreotide: major interaction.
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Résumé
Artemether/lumefantrine is known to prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. Together they may increase the risk of serious ventricular arrhythmias.
Ce que signifie cette interaction, en termes simples
Artemether / lumefantrine and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive QTc prolongation.
Conduite à tenir
Avoid the combination if feasible; if malaria treatment is essential, obtain an ECG, correct electrolytes and monitor for arrhythmia.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Octreotide
- Adagrasib + Octreotide Majeure
- Amisulpride + Octreotide Majeure
- Arsenic trioxide + Octreotide Majeure
- Artemether + Octreotide Majeure
- Ceritinib + Octreotide Majeure
- Disopyramide + Octreotide Majeure
Questions fréquentes
Can I take Artemether / lumefantrine with Octreotide?
MediHelp rates the interaction as major. Artemether / lumefantrine and Octreotide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Artemether/lumefantrine is known to prolong the QT interval, and octreotide may add to this through bradycardia and repolarization effects. Together they may increase the risk of serious ventricular arrhythmias.
How serious is the interaction between Artemether / lumefantrine and Octreotide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination if feasible; if malaria treatment is essential, obtain an ECG, correct electrolytes and monitor for arrhythmia.
What other medicines interact with Octreotide?
MediHelp also lists interactions of Octreotide with, for example, Adagrasib, Amisulpride, Arsenic trioxide. The full list is on the Octreotide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
